Oddball is the newest puppy. She is searching for her spots. Waddlesworth is a macaw who thinks he's a rottweiler. After a spot of therapy Cruella De Vil is released from prison and is a changed woman who is devoted to dogs and good causes. She is delighted that her parole officer, Chloe, has a dalmatian family and big connections with a dog charity. But the sound of Big Ben can reverse the treatment so it is only a matter of time before Cruella is back to her incredibly ghastly ways, using her new-found connections with Chloe and friends to get at the dalmatians.